翻訳と辞書 Words near each other ・ Prostitution by country ・ Prostitution in Afghanistan ・ Prostitution in Africa ・ Prostitution in ancient Greece ・ Prostitution in ancient Rome ・ Prostitution in Angola ・ Prostitution in Argentina ・ Prostitution in Armenia ・ Prostitution in Asia ・ Prostitution in Australia ・ Prostitution in Austria ・ Prostitution in Bahrain ・ Prostitution in Bangladesh ・ Prostitution in Belize ・ Prostacyclin receptor ・ Prostacyclin synthase ・ Prostaglandin ・ Prostaglandin analogue ・ Prostaglandin antagonist ・ Prostaglandin D2 ・ Prostaglandin D2 receptor ・ Prostaglandin D2 synthase ・ Prostaglandin DP1 receptor ・ Prostaglandin DP2 receptor ・ Prostaglandin E ・ Prostaglandin E synthase ・ Prostaglandin E1 ・ Prostaglandin E2 ・ Prostaglandin E2 receptor ・ Prostaglandin E3 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Prostacyclin synthase ： ウィキペディア英語版 Prostacyclin synthase Prostaglandin-I synthase () also known as prostaglandin I2 (prostacyclin) synthase (PTGIS) or CYP8A1 is an enzyme involved in prostanoid biosynthesis that in humans is encoded by the ''PTGIS'' gene. This enzyme belongs to the family of cytochrome P450 isomerases. == Function == This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostaglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.〔(【引用サイトリンク】 url =http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5740 )〕 Unlike most P450 enzymes, PGIS does not require molecular oxygen (O2). Instead it uses its heme cofactor to catalyze the isomerization of prostaglandin H2 to prostacyclin. Prostaglandin H2 is produced by cyclooxygenase in the first committed step of prostaglandin biosynthesis. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Prostacyclin synthase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.